Farm yields of soybeans have been relatively stagnant over the past two decades in Ontario. With higher commodity prices soybean growers are seeking solutions to overcome the limitations on soybean yields. Improving seed quality in the absence of any significant disease or pest pressure is also a challenge. Current agronomic recommendations in Ontario are based on research with relatively narrow objectives that focus on simple effects of a few factors at a time. Management needs to consider additive and synergistic effects on yield, seed quality, and profitability. This project studied the possible additive effects of inputs on different varieties as well as the effects of late maturing bean varieties for a given region. A “kitchen sink” approach was applied at the field scale level to assess the impacts of multiple inputs on soybean yields and seed quality. This treatment package was also broken down into its individual components and applied on 8 different varieties on small plots by the University of Guelph.